Table 1.

Maximal tension values (mg) induced by NA (1 μM), OA (1 μM), PMA (1 μM, in 1.5 mM Ca²⁺-containing or Ca²⁺-free medium) or high extracellular KCl concentration (60 mM) in intact and endothelium-denuded rat aortic rings in the absence and presence of GB (10 μM), TEA (2 mM) or ChTX (100 nM) plus apamin (500 nM)

	Control	+GB	+TEA	ChTX+apamin
With endothelium
NA	2264±131*	2146±178*	2359±171*	2293±182*
OA	2113±126*	2158±162*	2241±184*	2171±173*
PMA (0 mM Ca2+)	1874±98*	1950±141*	2011±154*	2043±160*
PMA	1941±109*	1878±111*	2105±169*	1933±125*
KCl	3372±163*,#	3260±261*,#	3351±265*,#	3289±271*,#
Without endothelium
NA	3087±175	3120±239	3174±248	3056±223
OA	2833±145	2780±206	2921±223	2987±210
PMA (0 mM Ca2+)	2684±149	2750±194	2791±234	2801±205
PMA	2721±152	2823±111	2851±215	2772±179
KCl	3827±195#	3798±272#	3921±293#	4002±265#

Each value is the mean±s.e.m. from ten (control) or five (GB, TEA or ChTX plus apamin) experiments. Levels of statistical significance:

^*P<0.01 versus the corresponding values in endothelium-denuded rat aortic rings;

^#P<0.05 with respect to the corresponding maximal tensions induced by NA (1 μM) in intact or endothelium-denuded aortic rings.