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Effect of (−) chromanol 293B on APD during β-adrenoceptor stimulation in beagle dog Purkinje fibres. (a) and (b) show representative action potentials recorded in fibres from female (F) and male (M) animals under control conditions, in the presence of 0.1 μM isoproterenol (Iso) with and without 10 μM (−) chromanol 293B (293B) at stimulation rates of 3.33 and 1.0 Hz.
