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. 2005 Nov 28;147(6):653–660. doi: 10.1038/sj.bjp.0706491

Table 1.

Effects of pacing rate, BaCl2 and (−) chromanol 293B on APD90 in beagle dog Purkinje fibres

Treatment Stimulation rate (Hz) Sex % Change in APD90 n Number of animals
Krebs buffera 3.33 Male −38.2±1.7 17 16
    Female −36.9±2.0NS 19 17
  0.2 Male 11.0±1.2 31b 24
    Female 16.2±1.3* 32b 28
           
BaCl2 (10 μM)c 3.33 Male 8.0±1.2 5 4
    Female 7.0±0.9NS 6 4
  1.0 Male 12.2±3.0 5 5
    Female 11.4±1.9NS 6 5
  0.2 Male 18.6±4.0 5 5
    Female 14.7±3.9NS 6 5
           
(−) chromanol 293B (10 μM)c 3.33 Male −0.6±1.2 4 4
    Female −0.2±0.6NS 4 4
  1.0 Male −0.2±0.7 4 4
    Female 1.4±1.3NS 4 4
  0.2 Male 0.2±1.3 4 4
    Female 1.8±2.2NS 4 4

APD90: the duration of action potential at 90% repolarisation. Data are expressed as mean±s.e.m.

a

Data are expressed as a per cent change relative to APD90 at 1.0 Hz in Krebs buffer.

b

Data were obtained in this study and Abi-Gerges et al. (2004a).

c

Data are expressed as a per cent change relative to APD90 at the same stimulation rate in Krebs buffer.

NS

P>0.05

*

P<0.01 versus values from male animals.