TABLE 1.
Parameters of the cell electroporation model
| Symbol | Value | Definition and source |
|---|---|---|
| a | 50 μm | Cell radius (44). |
| Cm | 10−2 F m−2 | Surface capacitance of the membrane (44). |
| gl | 2 S m−2 | Surface conductance of the membrane (44). |
| si | 0.455 S m−1 | Intracellular conductivity (44). |
| se | 5 S m−1 | Extracellular conductivity (44). |
| s | 2 S m−1 | Conductivity of the solution filling the pore (13). |
| Vrest | −0.08 V | Rest potential (62). |
| h | 5 × 10−9 m | Membrane thickness (39). |
| α | 1 × 109 m−2 s−1 | Creation rate coefficient (24). |
| Vep | 0.258 V | Characteristic voltage of electroporation (24). |
| N0 | 1.5 × 109 m−2 | Equilibrium pore density at Vm = 0 (24). |
| r* | 0.51 × 10−9 m | Minimum radius of hydrophilic pores (39). |
| rm | 0.8 × 10−9 m | Minimum energy radius at Vm = 0 (39). |
| q | ≡ (rm/r*)2 | Constant in Eq. 7 for pore creation rate (24). |
| D | 5 × 10−14 m2 s−1 | Diffusion coefficient for pore radius (11). |
| β | 1.4 × 10−19 J | Steric repulsion energy (12). |
| γ | 1.8 × 10−11 J m−1 | Edge energy (11,39). |
| σ0 | 1 × 10−6 J m−2 | Tension of the bilayer without pores (63). |
| σ′ | 2 × 10−2 J m−2 | Tension of hydrocarbon-water interface (64). |
| Fmax | 0.70 × 10−9 N V−2 | Max electric force for Vm = 1 V (31). |
| rh | 0.97 × 10−9 m | Constant in Eq. 10 for advection velocity (31). |
| rt | 0.31 × 10−9 m | Constant in Eq. 10 for advection velocity (31). |
| T | 310 K | Absolute temperature (37°C). |