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Anaesthetized rats comparisons of the effects of the nonselective 5-HT7 receptor agonist 5-CT given i.c.v. (a) alone and (b) in the presence of 5HT1B/1D receptor antagonist GR127935 on bladder contractions induced by saline infusion into the bladder; (c) shows the effect of the 5-HT1B receptor agonist CP-93,129 given i.c.v. again bladder contractions induced by saline infusion into the bladder (Read et al., 2004).
