| Growth factors |
| VEGF-165 |
DNA transfer of VEGF-165 into rat penis for neovascularization |
Burchardt et al. (2005) |
| VEGF with AAV-BDNF |
VEGF with adeno-associated virus-mediated brain-derived neurotrophic factor for ED treatment after cavernosal nerve injury |
Rogers et al. (2003) |
| NT3 gene |
Neurotrophin 3 gene, via HSV vector, showed some success with ED due to DM |
Bennett et al. (2005) |
| |
| Ion channels |
| Maxi-K+ channel |
Plasmid vector (hMaxi-K), which contains the hSlo gene, that encodes the alpha subunit of the Maxi K channel |
Christ (2002; 2004), Christ et al. (2004a), Melman et al. (2003; 2005) |
| |
| Nitric oxide |
| NOS isoforms |
Induce eNOS, nNOS, and iNOS to improve erectile function |
Gonzalez-Cadavid et al. (2004), Kendirci et al. (2005)
|
| |
| Neurotransmitters |
| VIP |
Some success transfecting penile corpora cavernosa with pcDNA3/vasoactive intestinal polypeptide (VIP) cDNA in streptozotocin (STZ)-diabetic rats |
Shen et al. (2005) |
| CGRP |
Data suggests that in vivo adenoviral gene transfer of CGRP improves erectile function in the aged rats |
Bivalacqua et al. (2001) |
