Figure 9.
Effects of ascending concentrations of TEA (1, 5 and 10 mM) on MIT in the continuing presence of paxilline (10 μM, panel a; n=4), IBTX (100 nM, panel b; n=7) and penitrem A (500 nM, panel c; n=5) on activity in quiescent mid-pregnant myometrial strips. MIT is normalized to that measured during an initial 7.5 min control period prior to application of the selective BKCa channel inhibitor; this essentially reflected basal tone during these periods, as spontaneous contractions were rare. *P<0.05.