Figure 1.

Effects of PKC inhibitors on LPS-induced NO production in J774 cells. J774 cells were stimulated by LPS (10 ng ml⁻¹) and treated with increasing concentrations of RO318220 (a), GÖ6976 (b) or LY333531 (c). After 24 h incubation, nitrite concentrations in the culture medium were measured as a marker of NO production. Values are mean±s.e.m. (n=6). ^**P<0.01 as compared with cells treated with LPS only.