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Effect of a P-selectin antagonist (rPSGL-Ig, 100 μg ml−1), a GPIIb–IIIa antagonist (Reopro, 100 nM), and a Pi3K inhibitor (LY294002, 100 μM) on thrombin-induced platelet P-selectin translocation (n=3–7) and GPIIb–IIIa activation (n=4–7) (*P<0.05 vs control, paired t-test).
