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Concentration–effect curves to ACh after the different in vivo treatments in wt mice
| Pharmacological parameters | Control (n=7) | Rosuvastatin (n=8) | Rosuvastatin-NTG (n=8) | NTG (n=7) |
|---|---|---|---|---|
| Maximal response (%) |
68±3 |
70±3 |
75±2 |
63±4 |
| pD2 value |
6.83±0.12 |
6.85±0.14 |
6.70±0.06 |
6.44±0.15 |
| AUC | 707±31 | 679±31 | 654±20 | 774±30 |
