Table 1.

Listing of randomized trials included in the meta-analysis of androgen treatment for muscle strength in older men.

Reference	N	Intervention & Baseline T ng/ml	Age (Mean Yrs.)	Design Quality*	Duration	Type of Strength Measure
22	38	Injection 100 mg biweekly; 5.9 ± NR	70	11	26 wks	Total body strength
23	10	Patch 5.0 mg Daily; NR	68	7	4 wks	Knee extension concentric
						Knee extension eccentric
						Knee flexion concentric
						Knee flexion eccentric
24	14	Injection 200 mg biweekly; 3.3 ± 0.5	67	11	12wks	Vertical step height
						Leg extensor
						Knee flexor
						Knee extensor
						Hand grip
25	12	Injection dosage adjusted; 3.9 ± 0.6	67	8	24 wks	Leg extension
						Leg curl
						Tricep extension
						Bicep curl
						Knee extension
26	67	Patch (2) 2.5 mg daily; 3.9 ± 1.7	76	9	52 wks	Leg extension
27	37	Gel 70 mg daily; 4.3 ± 0.9	68	7	12 wks	Shoulder non dominant
						Shoulder dominant extension
						Knee flexion dominant
						Knee extension dominant
						Knee flexion non dominant
						Knee extension non dominant
28	48	Injection 200 mg biweekly; 2.9 ± 0.5	71	9	156 wks	R hand grip
						L hand grip
						Ankle
						Knee
29	32	Injection 200 mg biweekly; 2.9 ± 0.3	66	8	52 wks	Hand grip
30	108	Patch 6 mg/day daily; 3.7 ± 0.8	>65	10	156 wks	Knee extension 60
						Knee extension 180
						Knee flexion 60
						Knee flexion 180
						Hand grip
31	13	Injection 100 mg weekly; 3.4 ± 0.1	67	8	12 wks	R hand grip
						L hand grip
32	76	Oral 80 mg twice a day; 4.9 ± 1.3	69	9	52 wks	R hand grip
						L hand grip
						Quadricep
						Calf

^*Score based on rating obtained from design quality form. Scores range from 0 to 13 with higher scores indicating better design quality. NR = not reported.