Table 2.
Regulation of Ca2+ spark and transient KCa current properties by caffeine
Control | Caffeine (10 μM) | |
---|---|---|
Ca2+ sparks | ||
Amplitude: all, nM | 1,915 ± 213 (33) | 1,375 ± 81*(42) |
Spread, μm2 | 2.92 ± 0.29 (20) | 3.61 ± 0.31*(20) |
Decay (t½), ms | 54.5 ± 3.9 (16) | 50.7 ± 5.7 (16) |
Coupling, % | 75.4 ± 4.9 | 75.8 ± 5.1 |
Global Ca2+, nM | 363 | 419 ± 9* |
KCa transient activity (NPo) | 15.5 ± 1.4 (25) | 15.7 ± 1.0 (32) |
Values are means ± SE of number of events in parentheses.
P < 0.05 vs. control.