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Production of IFNγ and IL4 by anti-CD3/CD28 stimulated peripheral blood T cells (mononuclear cells) from RA patients divided according to the Steinbrocker radiological damage scores on hand radiographs. The numbers of patients per group were: I=14, II=19, III=25, and IV=8. * Indicates a statistically significant difference between group III or IV and group I (p⩽0.05).
