Figure 1  .

Influence of dexamethasone or OX34 treatment, or both, on radiographic bone destruction of AA rats. Indicated is the mean radiographic score of both hindpaws, the SEM for each treatment group, and the levels of significance. Radiographic scores of two groups of 14 rats receiving either OX34 or control mAb are included from a previous study (Hoffmann et al, unpublished data). All mAb treatments were started with 2 mg followed by 1 mg intraperitoneally per injection day, mAb were given over three consecutive days unless stated otherwise; dexamethasone was given intraperitoneally at 1 mg/kg body weight either for two consecutive days starting on day 12 or 18 or once on day 15. * = mAb given two days and one day before induction of AA and on the day of induction. † = mAb given on day 15, 17, 20, and 23 after induction of AA.