Figure 2  .

Amelioration of established AA by dexamethasone plus OX34 mAb therapy. Ten animals with established AA were randomised to intraperitoneal injections of OX34 (n = 5) or istotype matched control mAb (AICD58.6, n = 5) over three consecutive days starting with a loading dose of 2 mg followed by 1 mg each at indicated time points (arrows). Dexamethasone was given intraperitoneally on day 15 at a dose of 1mg/kg body weight. Arthritis score was measured by a blinded investigator at indicated time points. Shown are means (SEM), arrows indicate mAb injections.