Figure 4 .
Frequency of serum IgG, IgA and IgM autoantibodies to Ro 60 kDa, Ro 52 kDa and La proteins in pSS and SLE patients by immunoblotting. The intensity of the signal in immunoblotting was semiquantified in relation to serial dilutions of chimeric anti-NIP antibody results. The following groups were established; for IgA 0.25-0.5 µg/ml (+), 0.5-1.0 µg/ml (++) and > 1.0 µg/ml (+++); for IgM 1.50-3.0 µg/ml (+), 3.0-6.0 µg/ml (++) and > 6.0 µg/ml (+++); for IgG 2.0-4.0 µg/ml (+), 4.0-8.0 µg/ml (++) and > 8.0 µg/ml (+++). The horizontal lines indicates median values.