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Dependence of ADPNP-induced cleavage on DNA topology
| DNA topological form | Cleavage efficiency %
|
Ratio | |
|---|---|---|---|
| −ADPNP | +ADPNP | ||
| −ve s/c | 0.16 ± 0.07 | 1.22 ± 0.20 | 7.6 ± 2.0 |
| Relaxed | 0.19 ± 0.04 | 0.58 ± 0.10 | 3.1 ± 0.5 |
| +ve s/c | 0.49 ± 0.20 | 0.68 ± 0.02 | 1.4 ± 0.3 |
Results are reported as the average of a number of different experiments; errors express the range of experimental values.
