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. 2000 Feb;59(2):125–131. doi: 10.1136/ard.59.2.125

Figure 2  .

Figure 2  

Characteristics of [125I]351A binding to human synovium. (A) Association (filled circles) and dissociation (empty circles) at 22°C of 0.03 nM [125I]351A binding to blood vessels in synovia from patients with rheumatoid arthritis. For dissociation time course, sections were transferred to an excess of buffer without [125I]351A at 180 minutes (arrow). (B) Inhibition of 0.03 nM [125I]351A binding to blood vessels in synovia from patients with rheumatoid arthritis by unlabelled lisinopril (circles) or captopril (triangles). (C) Saturation of [125I]351A binding to blood vessels in synovia from patients with rheumatoid arthritis. (D) Saturation of [125I]351A binding to synovial stroma from patients with rheumatoid arthritis (filled circles) or osteoarthritis (empty circles). Points represent means (SEM) for synovia from six to eight patients.