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. 2000 Feb;59(2):135–140. doi: 10.1136/ard.59.2.135

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MRI and SJ biopsy specimen of a 35 year old man HLA B27+ uSpA patient with a disease duration of 1.8 years and severe IBP. (A) STIR sequence showing definite acute changes in the right sacroiliac joint (chronicity grade I, activity grade b) compared with a normal left side. The bone marrow osteitis and bone marrow oedema are clearly seen on both sides of the right sacroiliac joint (asterisks). (B) The biopsy specimen shows a cellular infiltrate (white arrow), containing CD3+ T lymphocytes that seem to invade a cartilagineous area with a chondroclast (black arrow) and hypertrophic chondrocytes (immunohistology/haematoxylin and eosin staining, original magnification × 500).

MRI and SJ biopsy specimen of a 35 year old man HLA B27+ uSpA patient with a disease duration of 1.8 years and severe IBP. (A) STIR sequence showing definite acute changes in the right sacroiliac joint (chronicity grade I, activity grade b) compared with a normal left side. The bone marrow osteitis and bone marrow oedema are clearly seen on both sides of the right sacroiliac joint (asterisks). (B) The biopsy specimen shows a cellular infiltrate (white arrow), containing CD3+ T lymphocytes that seem to invade a cartilagineous area with a chondroclast (black arrow) and hypertrophic chondrocytes (immunohistology/haematoxylin and eosin staining, original magnification × 500).

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