Skip to main content
. 1999 Jul 20;96(15):8449–8454. doi: 10.1073/pnas.96.15.8449

Figure 4.

Figure 4

Schematic of HPV 31 E7 mutants. Mutation sites are indicated by arrows. E7–3XTAA represents a translation termination mutant with a substitution of amino acids 9–11 with three stop codons. E7–D21G and E7–C24G indicate mutations in the DLXCXE Rb-binding motif at the indicated amino acids. E7–R2P represents a transformation-defective mutant at amino acid 2, and E7–CK2 denotes a potential CK2 phosphorylation site mutant with substitutions of amino acids 32 and 33. All mutants were generated in the context of the pBR322.HPV31 construct. Shaded areas indicate the zinc finger regions of the protein.