Figure 1  .

Effect of aminoguanidine (AG) and hydrocortisone (Hydro) on the release of interleukin 1β (IL1β) and nitric oxide (NO) in the media of lipopolysaccharide (LPS) stimulated synovial tissue cultures. Bars show the mean and SEM of three separate experiments. The absolute mean (SEM) levels of IL1β in control and in LPS stimulated cultures were 7.3 (0.89) and 14.9 (2.5) pg/mg synovia, respectively. The absolute mean (SEM) levels of NO in control and LPS stimulated cultures were 2.13 (0.2) and 4.34 (0.19) µmol/mg synovial tissue, respectively.