Figure 3 .
In vitro effect of prednisolone sodium succinate (PRED) on the activity of calcineurin in peripheral blood mononuclear cells (PBMC) of healthy subjects. PBMC of five healthy controls were cultured for 72 hours in the absence and presence of 10−4 M PRED. Calcineurin activities were determined and the statistical analysis was carried out as described in "Patients and methods". Asterisks denote significant differences compared with the respective controls. For the calculation of statistical significance Student's paired t test was used.