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Intracellular cAMP levels. Basal cAMP levels (cAMP basal) were significantly raised in patients with systemic lupus erythematosus (SLE) compared with control subjects. The relative increase of cAMP (% increase cAMP) above basal levels after isoprenaline stimulation was markedly decreased in both patient groups compared with the control group (* p<0.05, ** p<0.001; one way analysis of variance followed by Tukey's procedure; RA, SLE v control).
