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Levels of U-CTX-II, U-Glc-Gal-PYD, and S-PIIINP according to quartiles of joint space area (JSA) of the knee. A total of 134 knees were analysed. Bars represent the mean value (SEM) of the biochemical marker in each quartile of JSA. p Values apply to the comparison of trend in biochemical marker levels for increasing JSA, assessed by analysis of variance.
