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Arthritis in B6.IFNγ KO mice immunised with bovine CII in CFA. (A) An arthritic hind paw of a B6.IFNγ KO mouse at day 3 of arthritis with a clinical score 1. There is substantial erythematous oedema from the ankle through the digits. Note the marked swollen tarsal and metatarsal joints. This is the typical sign of an arthritic paw seen in CIA in DBA/1 mice. (B) Normal appearance of a non-arthritic hind paw of a B6 mouse immunised with bovine CII in CFA.
