Figure 1.

Effect of histamine on the proliferative rate of HAC in vitro. (A) Effect of different histamine concentrations (1–100 µmol/l) on cell proliferation after six days. Preparation HAC2, passage 2. Data represent intra-assay values, showing mean (SEM) of eight wells for each treatment. (B) Effect of histamine (20 µmol/l) on cell proliferation of five different HAC cultures after six days. Data represent intra-assay values, showing mean (SEM) of eight wells for each treatment. (C) Averaged data from five HAC cultures with or without histamine (20 µmol/l). Data represent the mean (SEM) of the five HAC cultures presented in (B). **p=0.00012, Student's t test.