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. 2003 Mar;62(3):196–203. doi: 10.1136/ard.62.3.196

Figure 3.

Figure 3

Immunolocalisation of MMP-2 and MMP-9 in RA synovial tissue at the bone-cartilage interface. (A and D) TRAP staining, serial section. Mononuclear (arrows) and multinucleated cells (arrowheads) in RA synovial tissue at the bone-cartilage interface display TRAP activity. (B and E) Immunohistochemistry for MMP-2 and MMP-9. The TRAP positive mononuclear and multinucleated cells shown in A and D express MMP-2 and MMP-9. (C and F) Isotype controls for B and E. Haematoxylin counterstaining was performed in B, C, E, and F. Bar = 100 µm.