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(A) TNFα concentrations at 24 hours in culture media after incubation of RA synovial macrophages with A77 1726 at concentrations of 1, 10, and 30 µmol/l. *p<0.05; **p<0.01 versus controls. (B) IL1ß concentrations at 24 hours in culture media after incubation of RA synovial macrophages with A77 1726 at concentrations of 1, 10, and 30 µmol/l. No significant changes were found.
