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. 2003 Jun;62(6):561–564. doi: 10.1136/ard.62.6.561

Figure 2.

Figure 2

A significant increase in the production of IFNγ and of TNFα by CD8+ T cells upon PMA/ionomycin stimulation is seen during etanercept treatment. No change in the cytokine production was detected after six weeks of treatment in the placebo group, but a significant increase in the production of IFNγ and of TNFα by CD8+ T cells upon PMA/ionomycin stimulation was seen after the patients were switched to etanercept treatment. The median and range of non-specific cytokine production are indicated in the figure. *p<0.05 compared with before treatment; #p=0.008 compared with before treatment.