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Treatment of either PBMC or EC with LEF-M decreases the transendothelial migration of PBMC. Preincubation for 24 hours of PBMC or EC or PBMC and EC with 100 µM LEF-M induced a significant decrease in the percentage of migrated cells (PBMC 39 (9)% v 48 (6)%, p<0.005; EC: 36 (16)% v 48 (6)%, p<0.05).
