Figure 1.

 Incidence of 30%, 50%, and 70% improvement in patients with juvenile idiopathic arthritis (JIA) receiving etanercept treatment, according to the core set criteria. Data on 275 patients are included. Analysis was undertaken by LCOF (last observation carried forward). (A) 48 JIA patients with systemic onset and a treatment duration of at least two months. Four patients were excluded because treatment had been discontinued earlier; in eight patients month 1 data were missing; eight patients with systemic onset JIA discontinued treatment prematurely. At last report, a 30%, 50%, or 70% response level was reported in one, one, and two patients, respectively, while four were non-responders. (B) 222 JIA patients with non-systemic-onset. In 32 patients month 1 data were missing. The number of non-systemic-onset JIA patients who met the 30%, 50% and 70% response criteria exceeded the number of systemic onset JIA patients who met the core set criteria. Twenty four of 222 patients with non-systemic-onset JIA discontinued prematurely. At last report a 30%, 50%, or 70% response level was reported in four, six, and eight patients, while only six were non-responders.