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Th1 immune modulation in patients with RA, healthy controls, and our patient. PBMC from the patient (black bar), control patients with RA (n = 15, grey bar), and healthy controls (n = 14, white bar), were stimulated with or without 1 ng/ml IL12 or a combination of IL12 (1 ng/ml) and IL18 (5 ng/ml). IFNγ concentrations in culture supernatants were measured by ELISA.
