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. 2005 Apr 7;64(11):1542–1549. doi: 10.1136/ard.2004.032599

Figure 2.

Figure 2

 Immunoreactivity of trkA (A–C) and NGFRp75 (D–F) in the lining layer, sublining layer, and endothelium of synovial tissue biopsy specimens obtained from clinically affected knee joints of 24 patients with SpA, 15 with RA, and 10 with OA. The results represent the individual scores on a semiquantitative 0 (no expression) to 3 (high expression) scale, with bars representing the median score. As indicated (*), the immunoreactivity of trkA was significantly higher in SpA lining than in RA lining (p = 0.047) and OA lining (p = 0.034). Similarly, trkA was more highly expressed in SpA and RA sublining than in OA (p = 0.001 and p = 0.003, respectively). NGFRp75 was almost absent in the lining layer and was equally expressed across disease groups in the sublining layer. However, some patients with SpA showed high endothelial expression, resulting in a significant difference in comparison with RA (p = 0.012) and OA (p = 0.041).