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ß-Gal expression in rat synovial tissue 1, 2, 3, and 4 weeks after intra-articular (IA) injection of 1.14x1010 GC rAAV serotype 2 or 5, quantified by digital image analysis. Injected joints were snap frozen and cryosections were stained in situ for ß-Gal activity. Staining was evaluated by computer assisted analysis and expressed as IODx10/mm2.
