Box and whisker plots: boxes signify 25th and 75th centiles, whiskers 10th and 90th centiles, crosses are means, dots are outliers. Comparisons were made between disease groups. Means and medians are given, as well as p values for parametric (ANOVA) and non-parametric (Kruskal–Wallis) analyses. Granzyme B values (for patients with levels >10 pg/ml) are computed as log granzyme concentrations in pg/ml. RA, rheumatoid arthritis; SpA, spondylarthropathy; UA, undifferentiated arthritis.