Skip to main content

Figure 1.

Figure 1

 SNPs in MHC2TA pIII and coding region. (A) Genomic DNA was isolated from peripheral blood mononuclear cells, and PCR and direct sequencing were performed with eight oligonucleotide primer sets for genomic analysis of SNPs (arrows). (B) MHC2TA promoter elements and exon organisation. Arrows on the box represent upstream regulatory sequences for each promoter. Promoter pI is used primarily by dendritic cells, pIII by B cells, and pIV for IFNγ-inducible CIITA expression by non-professional APCs.