Figure 1.

 Mean changes in disease activity and ultrasonographic variables over time in rheumatoid and psoriatic refractory knee joint synovitis (KJS). (A) systemic disease activity measurements. (B) local disease activity and ultrasonographic measurements. CRP, C reactive protein; ESR, erythrocyte sedimentation rate; F/SI-PD, fluid/synovium interface power Doppler flow configuration; GHS, global health status; KJAI, knee joint articular index; P/CI-PD, pannus/cartilage interface power Doppler flow configuration; RAI, Ritchie articular index; ST–US, synovial thickness measured by ultrasound.