Histology score of AbIA mice. The extent of cellular infiltration in AbIA mice treated with PLGA-nanosteroid (30 µg x1, IV), BSP (30 µg, x3, IV), or vehicle-PLGA nanoparticles was determined and graded from 0 to 3 in each paw. Data represent mean (SEM) (seven mice in each group). *p<0.05 (PLGA-nanosteroid v BSP); †p<0.01 (PLGA-nanosteroid v vehicle-PLGA nanoparticles).