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Dose-response curve of IL6 production by myoblasts stimulated with increasing concentrations of TNFα or IL1ß in the presence or not of a soluble receptor (sR). Myoblasts were incubated with increasing concentrations (pg/ml) of TNFα (A) or IL1ß (B). Myoblasts were also incubated with the same increasing concentrations of cytokine and 1 µg/ml of their respective sR, p75 TNFα sR, and type II IL1ß sR. IL6 levels were measured by ELISA in 48 hour supernatants.
