Table 1.
Aptamer | Variable Region |
---|---|
C1 | EWCGPCESCQILFLQFRCLRFCRRMGPCKM |
C2 | EWCGPLHSSELECRISGFLSVSMLLGPCKM |
C3 | EWCGPRLRAQRRDWVHCTGIRQYVGGPCKM |
C4 | EWCGPEMYQVFLWIQGCLDHRPGMPGPCKM |
C5 | EWCGPCMTCKIQQLLNVPDVAPGCSGPCKM |
C6 | EWCGPWNSWFVLYDGRVKWCMREGGGPCKM |
C7 | EWCGPFADEWPYQRRWFWTIVEVDSGPCKM |
N1 | EWCGPVLDYFWPVWGLCQWHALLMTGPCKM |
N2 | EWCGPRLQAWTLGARGFVILASLFSGPCKM |
N3 | EWCGPWLVAYLSGHTRTWWAPGNFMGPCKM |
N4 | EWCGPTLRWWVYWSGCSNHPFSILSGPCKM |
N5 | EWCGPQKVTSMEINLGFLLGVWSWGGPCKM |
Variable regions of aptamers that break α-factor arrest. Sequence of these variable regions is shown in bold, flanked by 5 aa on each side from the thioredoxin platform. The letters C and N refer to aptamers that were isolated from the nonlocalized and nuclear localized libraries, respectively.