Table 2.
RH mapping of candidates genes for PCOS
| Gene* | Chromosomal location | Linked marker | Logarithm of odds† | STRP marker for linkage analysis | Distance between STRP and candidate gene, cM |
|---|---|---|---|---|---|
| FS | 5p14 | SHGC-36388 | 13.8 | D5S623 | <0.5 |
| SHBG | 17p13.2 | SHGC-35513 | 8.5 | D17S1353 | <1.0 |
| INHA | 2q36.1 | SHGC-11864 | 1,000 | D2S163 | <1.0 |
| INHC | 12q13 | AFM312XF5 | 11.5 | D12S1691 | <1.0 |
| ACTR1 | 12q13.12 | AFM298ZB1 | 9.4 | D12S347 | <0.8 |
| ACTR2A | 2q22.2 | SHGC-9391 | 10.3 | D2S2335 | <1.0 |
| ACTR2B | 3p22.2 | SHGC-115353 | 9.7 | D3S1298 | <1.0 |
| MADH4 | 18q21 | SHGC-33967 | 1,000 | D18S474 | <1.0 |
*Abbreviations are defined in Table 1.
†
Two-point maximum logarithm of odds score between candidate gene and most closely linked marker.