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. 1999 Jul 20;96(15):8573–8578. doi: 10.1073/pnas.96.15.8573

Table 3.

Results from the present study for linkage and TDT analysis of genes previously tested in other studies

Gene (ref.) ASP Analysis
TDT
IBD Not IBD Total, n IBD, % χ2 P Allele Transmitted Not transmitted χ2 P
INS VNTR (35,36) Class III
15.2 14.8 30 51 0.00 >0.5  Total 50 54 0.15 >0.5
 Paternal 23 24 0.02 >0.5
 Maternal 27 30 0.16 >0.5
CYP11A (10)
D15S519 22.8 14.2 37 62 2.03 0.15  7 73 90 1.77 0.18
D15S520 21 12.7 33.7 62 2.06 0.15  5 72 82 0.65 0.42
 Haplotype* 30.8 15.2 46 67 5.34 0.02
CYP19 (10)
25.9 24.7 50.7 52 0.03 <0.5  6 56 36 4.35 0.04
 7 20 40 6.67 0.01
CYP17 (11,37)
D10S192 28.5 29.5 58 49 0.02 >0.5 10 27 50 6.87 0.01
INSR (18–20)
INSR 17.5 12.5 30 58 0.83 0.36 13 39 21 5.40 0.02
D19S884 27.3 24.7 52 53 0.14 >0.5  5 10 28 8.53 0.004
 Haplotype 34.7 29.9 64.7 54 0.36 >0.5

*D15S519–D15S520. 

pterD19S905–INSR–D19S884–D19S922cen.