Table 3.
Gene (ref.) | ASP Analysis
|
TDT
|
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
IBD | Not IBD | Total, n | IBD, % | χ2 | P | Allele | Transmitted | Not transmitted | χ2 | P | |
INS VNTR (35,36) | Class III | ||||||||||
15.2 | 14.8 | 30 | 51 | 0.00 | >0.5 | Total | 50 | 54 | 0.15 | >0.5 | |
Paternal | 23 | 24 | 0.02 | >0.5 | |||||||
Maternal | 27 | 30 | 0.16 | >0.5 | |||||||
CYP11A (10) | |||||||||||
D15S519 | 22.8 | 14.2 | 37 | 62 | 2.03 | 0.15 | 7 | 73 | 90 | 1.77 | 0.18 |
D15S520 | 21 | 12.7 | 33.7 | 62 | 2.06 | 0.15 | 5 | 72 | 82 | 0.65 | 0.42 |
Haplotype* | 30.8 | 15.2 | 46 | 67 | 5.34 | 0.02 | — | — | — | — | — |
CYP19 (10) | |||||||||||
25.9 | 24.7 | 50.7 | 52 | 0.03 | <0.5 | 6 | 56 | 36 | 4.35 | 0.04 | |
7 | 20 | 40 | 6.67 | 0.01 | |||||||
CYP17 (11,37) | |||||||||||
D10S192 | 28.5 | 29.5 | 58 | 49 | 0.02 | >0.5 | 10 | 27 | 50 | 6.87 | 0.01 |
INSR (18–20) | |||||||||||
INSR | 17.5 | 12.5 | 30 | 58 | 0.83 | 0.36 | 13 | 39 | 21 | 5.40 | 0.02 |
D19S884 | 27.3 | 24.7 | 52 | 53 | 0.14 | >0.5 | 5 | 10 | 28 | 8.53 | 0.004 |
Haplotype† | 34.7 | 29.9 | 64.7 | 54 | 0.36 | >0.5 | — | — | — | — | — |
*D15S519–D15S520.
pterD19S905–INSR–D19S884–D19S922cen.