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. 1999 Jul 20;96(15):8579–8584. doi: 10.1073/pnas.96.15.8579

Figure 3.

Figure 3

Physiological analysis of Tg mice (FVB/N background) that ubiquitously express wild-type agouti (BAPa) or agoutiΔbasic (BAPaΔbasic). The numbers 43, 38, and 41 refer to the three lines of BAPaΔbasic Tg mice. BAPa data were derived from the BAPa20 Tg line (12). All data were obtained from Tg and non-Tg male littermates. The two asterisks (∗∗) indicate that the means for Tg versus non-Tg mice differ significantly (P < 0.01). (A) Mean body weight (in grams) ± SEM at 24 weeks of age. The number of mice in each category are BAPa Tg/− (n = 11), control (n = 53); BAPaΔbasic-43 Tg/− (n = 15), control (n = 35); BAPaΔbasic-38 Tg/− (n = 8), control (n = 8); and BAPaΔbasic-41 Tg/− (n = 18), control (n = 22). (B) Mean insulin levels (in microunits of insulin per milliliter of plasma) ± SEM of mice at least 24 weeks of age. The number of mice in each category are BAPa20 Tg/− (n = 10), control (n = 46); BAPaΔbasic-43 Tg/− (n = 8), control (n = 8); BAPaΔbasic-38 Tg/− (n = 4), control (n = 4); and BAPaΔbasic-41 Tg/− (n = 13), control (n = 8). (C) Mean glucose levels (milligrams of glucose per deciliter of whole blood) ± SEM of mice at least 24 weeks of age. The number of mice in each category are BAPa20 Tg/− (n = 5), control (n = 20); BAPaΔbasic-43 Tg/− (n = 10), control (n = 8); BAPaΔbasic-38 Tg/− (n = 7), control (n = 7); and BAPaΔbasic-41 Tg/− (n = 14), control (n = 8).