Table 4.

LNC from mL9-immunized mice reject tumor cells made insensitive to IFN-γ (PRO-DNγR), but still require IFN-γ for this effect

LNC*	Antibody treatment†	Tumor incidence after 28 days‡
−	—	5/5
+	—	0/5
+	Anti-IFN-γ	2/12

^*SCID mice were inoculated s.c. with PRO-DNγR tumor cells and received LNC from mL9-immunized mice. 

^†An additional animal treated with LNC and also with anti-IL-4 antibody rejected the tumor cell challenge similar to the LNC-treated mice treated with anti-IL-4 in Table 3. 

^‡The tumor incidence of PRO-DNγR for LNC-treated versus untreated mice was stitistically significant (P value = 0.008) by Fisher’s Exact test. The difference between tumor incidence for LNC-treated and LNC-treated plus anti-IFN-γ antibody is also statistically significant (P value = .048) by Fisher’s Exact test.