Figure 5.

Quantitation of injury cavity in mice after controlled cortical impact brain injury. (A) Cavity area was calculated from hematoxylin and eosin-stained coronal sections from −1.5 to 4.35 mm posterior to bregma for wt (squares) and TNF (−/−) (triangles)at 4 weeks postinjury. Symbols represent mean areas; error bars denote SD. ∗, P < 0.05 (B) Lesion volume was calculated at 1,2, and 4 weeks postinjury. Mean volumes are presented for wt mice (open bars) and TNF(−/−) mice (filled bars). Error bars depict SD. ∗∗, P < 0.005; ∗, P < 0.05 when compared with wild-type mice.