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. 2000 Dec 20;2(1):research0002.1–research0002.10. doi: 10.1186/gb-2000-2-1-research0002

Table 3.

Strength of RNAi by feeding versus injection

Feeding Injection


Test gene n % Phe n % Phe
gpb-1 506 100 175 100
par-1 262 100 293 100
par-2 257 100 288 100
par-3 241 97 540 100
par-6 361 100 348 100
cyk-1 308 55 275 100
skn-1 355 100 311 100
dnc-1 343 100 309 100
bir-1 391 100 403 100
pal-1 393 100 396 100
dif-1 391 100 244 100
plk-1 402 100 239 100
dhc-1 269 100 173 100
mex-3 200 100 256 100

Fourteen known maternal-effect embryonic lethal genes were tested to determine the efficiency of RNAi by feeding relative to injection for producing embryonic lethality. Data shown represent the progeny of three fed worms. n, number of embryos scored; %Phe, percentage of embryos with embryonic lethality.

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