Geometry control during fabrication by using laminar flows.
(a) A schematic of the fabrication method using laminar
flows to control geometry. (b) Steady laminar flows are
obtained before UV irradiation. The outer streams of prepolymer mixture
contain acrylic acid, EGDMA, water, and a photoinitiator. The middle
stream consists of glycerin. The channel fabrication is the same as
described in Fig. 5a. (c) After UV
irradiation for 2 min, pH-sensitive hydrogel walls are formed while the
center of the channel remains open. (d) When exposed to
a basic solution, the pH-sensitive hydrogels expand to seal off the
channel. (Bars = 500 μm.)