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. 1999 Oct;82(4):e4. doi: 10.1136/hrt.82.4.e4

Heart transplant for dilated cardiomyopathy associated with polymyositis

A Afzal, R Higgins, E Philbin
PMCID: PMC1760297  PMID: 10490578

Abstract

Cardiac involvement is one of the most significant factors in the poor clinical outcome of polymyositis. The case of a 39 year old African American woman with polymyositis, cardiomyopathy, and severe heart failure who had orthotopic heart transplantation is described. Review of the literature reveals that cardiac manifestations of polymyositis are frequent and include conduction system abnormalities, myocarditis, cardiomyopathy, coronary artery atherosclerosis, valvar disease, and pericardial abnormalities.


Keywords: polymyositis; cardiomyopathy; heart failure; heart transplantation

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Figure 1  .

Figure 1  

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Admission 12 lead ECG.

Figure 2  .

Figure 2  

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Admission chest radiograph, anteroposterior view.

Figure 3  .

Figure 3  

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Biopsy of explanted heart, haematoxylin and eosin stain.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Askari A. D. Inflammatory disorders of muscle. Cardiac abnormalities. Clin Rheum Dis. 1984 Apr;10(1):131–149. [PubMed] [Google Scholar]
  2. Bohan A., Peter J. B., Bowman R. L., Pearson C. M. Computer-assisted analysis of 153 patients with polymyositis and dermatomyositis. Medicine (Baltimore) 1977 Jul;56(4):255–286. doi: 10.1097/00005792-197707000-00001. [DOI] [PubMed] [Google Scholar]
  3. Denbow C. E., Lie J. T., Tancredi R. G., Bunch T. W. Cardiac involvement in polymyositis: a clinicopathologic study of 20 autopsied patients. Arthritis Rheum. 1979 Oct;22(10):1088–1092. doi: 10.1002/art.1780221007. [DOI] [PubMed] [Google Scholar]
  4. Gottdiener J. S., Sherber H. S., Hawley R. J., Engel W. K. Cardiac manifestations in polymyositis. Am J Cardiol. 1978 Jun;41(7):1141–1149. doi: 10.1016/0002-9149(78)90871-8. [DOI] [PubMed] [Google Scholar]
  5. Lynch P. G. Cardiac involvement in chronic polymyositis. Br Heart J. 1971 May;33(3):416–419. doi: 10.1136/hrt.33.3.416. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Oka M., Raasakka T. Cardiac involvement in polymyositis. Scand J Rheumatol. 1978;7(4):203–208. doi: 10.3109/03009747809095655. [DOI] [PubMed] [Google Scholar]
  7. Stern R., Godbold J. H., Chess Q., Kagen L. J. ECG abnormalities in polymyositis. Arch Intern Med. 1984 Nov;144(11):2185–2189. [PubMed] [Google Scholar]

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