Figure 3.

Mecamylamine effects on α1β1γδ and α1β1(β4TM2)γδ receptors. The effects of 1 μM mecamylamine, co-applied with 10 μM ACh were measured during the co-application response (t=0) and for a subsequent response to 10 μM ACh alone (t=5). Experimental responses were normalized to the cells' initial control ACh responses. The co-application of 1 μM mecamylamine produced a significant decrease in the responses of α1β1(β4TM2)γδ receptors (P<0.01). Each bar represents the average normalized response of four cells (±s.e.mean).