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Blocking actions of KN244 on the response of expressed RDL homo-oligomers to GABA. (a) Dose-response curves for GABA on wild-type RDL receptors are shown in the absence and presence of KN244 (2.7 μM). (b) Actions of KN244 on the responses to 30 μM GABA of wild-type and mutant homo-oligomers. Each point plotted is the mean of 3–6 observations, and vertical bars represent±one standard error of the mean.
